原花青素 B2
原花青素B2(Procyanidin B2)
CAS: 29106-49-8
化学式: C30H26O12
| 中文名 | 原花青素B2 |
| 英文名 | Procyanidin B2 |
| 别名 | 原花青素B2 原矢车菊素B2 原花青素 B2 原花青素B2对照品, 原花青素B2(标准品) 原花青素B2(2-8℃) 4,8″-二-[(+)-表儿茶素] 顺式,顺式″-4,8″-二(3,3′,4′,5,7-五羟基黄烷) |
| 英文别名 | Procyanidin B2 PROCYANIDIN B2 4,8'-BI-[(+)-EPICATECHIN] EPICATECHIN(4B-8)EPICATECHIN CIS,CIS'-4,8'-BI(3,3',4',5,7-PENTAHYDROXYFLAVANE) 4,8-Bi-[(+)-epicatechin], cis,cis-4,8-Bi(3,3μ,4μ,5,7-pentahydroxyflavane) (2R,2'R,3R,3'R,4R)-2,2'-Bis(3,4-dihydroxyphenyl)-4,8'-bichroman-3,3',5,5',7,7'-hexol |
| CAS | 29106-49-8 |
| 化学式 | C30H26O12 |
| 分子量 | 578.52 |
| InChIKey | XFZJEEAOWLFHDH-NFJBMHMQSA-N |
| 密度 | 1.705 |
| 熔点 | 197-198℃ |
| 沸点 | 955.3±65.0 °C(Predicted) |
| 比旋光度 | +26 (H2O) |
| 溶解度 | DMSO (微溶) 、乙醇 (微溶) 、甲醇 (微溶) |
| 酸度系数 | 9.29±0.60(Predicted) |
| 存储条件 | Inert atmosphere,2-8°C |
| 外观 | 整洁 |
| 颜色 | Light Red to Brown |
| 物化性质 | 来源于提取自葡萄籽 |
| MDL号 | MFCD01861513 |
| 安全术语 | S22 - 切勿吸入粉尘。 S24/25 - 避免与皮肤和眼睛接触。 |
| WGK Germany | 3 |
| 参考资料 展开查看 | 1. 张璐 潘佩佩 陈赛贞. RP-HPLC法同时测定原花青素中儿茶素、表儿茶素、没食子酸、原花青素B_2的含量[J]. 中国药科大学学报 2016 v.47(01):54-57. 2. 杨博, 鄢又玉, 钟方旭,等. 火棘果中原花青素提取工艺优化[J]. 中国食物与营养, 2011, 17(005):60-66. 3. 朱月, 张海平+, 侯亚男,等. 黑果腺肋花楸原花青素的纯化及表儿茶素和原花青素B_2含量测定[J]. 食品工业科技, 2017(19):246-250. 4. 陈晓静 何杰 杨建云 等. RP-HPLC法同时测定葡萄籽提取物中没食子酸 儿茶素和表儿茶素的含量[J]. 药物分析杂志 2015 035(004):723-727. 5. 杨代晓, 陈晓静, 胡秋菊,等. 液相色谱-质谱联用法分析葡萄籽提取物中的5种多酚类成分[J]. 药物分析杂志, 2016(8):1330-1337. 6. 周婷, 雷润梅, 赵晓丹,等. 花生红衣中B型二聚体原花青素对丙烯酰胺的抑制效果[J]. 现代食品科技, 2016(10):66-71. 7. 毛雪, 刘玉梅. 葡萄枝蔓中原花色素的不同分析方法比较及含量分析[J]. 食品科学, 2016, 37(12):169-175. 8. 陈希苗, 李美英, 许秋莉,等. 体外模拟胃肠消化中山楂多酚及抗氧化活性的变化[J]. 食品科学, 2019, 040(005):31-37. 9. 旷慧, 冯建文, 范倩,等. 红树莓多酚的组分分析及体外抗脂质过氧化活性[J]. 食品科学, 2018, 39(003):83-89. 10. 田莉, 李海萍, 袁亚宏,等. 真空耦合超声波提取苹果渣多酚的工艺优化[J]. 食品科学, 2017(14):240-246. 11. 黑青稞麸皮结合态酚类物质大孔树脂分离纯化工艺优化 12. Zhang, L., Tai, Y., Wang, Y. et al. The proposed biosynthesis of procyanidins by the comparative chemical analysis of five Camellia species using LC-MS. Sci Rep 7, 46131 (2017). https://doi.org/10.1038/srep46131 13. Su, Dongxiao, et al. "Impact of thermal processing and storage temperature on the phenolic profile and antioxidant activity of different varieties of lychee juice." LWT 116 (2019): 108578.https://doi.org/10.1016/j.lwt.2019.108578 14. Wang, Zhineng, et al. "Comparison of the phenolic profiles and physicochemical properties of different varieties of thermally processed canned lychee pulp." RSC Advances 10.12 (2020): 6743-6751.10.1039/C9RA08393F 15. Zhang, Minmin, et al. "Chemical characterization and evaluation of the antioxidants in Chaenomeles fruits by an improved HPLC-TOF/MS coupled to an on-line DPPH-HPLC method." Journal of Environmental Science and Health, Part C 36.1 (2018): 43-62.https://doi 16. [IF=5.742] Ya-Wei Xing et al."Procyanidin B2 protects against diet-induced obesity and non-alcoholic fatty liver disease via the modulation of the gut microbiota in rabbits."World J Gastroentero. 2019 Feb 28; 25(8): 955–966 17. [IF=5.657] Hongming Su et al."Procyanidin B2 ameliorates free fatty acids-induced hepatic steatosis through regulating TFEB-mediated lysosomal pathway and redox state."Free Radical Bio Med. 2018 Oct;126:269 18. [IF=5.396] Lin Han et al."Proanthocyanidin B2 attenuates postprandial blood glucose and its inhibitory effect on alpha-glucosidase: analysis by kinetics, fluorescence spectroscopy, atomic force microscopy and molecular docking."Food Funct. 2018 Sep;9(9):4673-4682 19. [IF=5.396] Jiachan Zhang et al."Understanding the role of extracts from sea buckthorn seed residues in anti-melanogenesis properties on B16F10 melanoma cells."Food Funct. 2018 Oct;9(10):5402-5416 20. [IF=5.279] Suwen Liu et al."Hawthorn Polyphenol Extract Inhibits UVB-Induced Skin Photoaging by Regulating MMP Expression and Type I Procollagen Production in Mice."J Agr Food Chem. 2018;66(32):8537–8546 21. [IF=4.379] Zhang Liang et al."The proposed biosynthesis of procyanidins by the comparative chemical analysis of five Camellia species using LC-MS."Sci Rep-Uk. 2017 Apr;7(1):1-10 22. [IF=3.757] Yuchen Wang et al."Metabolic profile of ginkgo kernel juice fermented with lactic aicd bacteria: A potential way to degrade ginkgolic acids and enrich terpene lactones and phenolics."Process Biochem. 2019 Jan;76:25 23. [IF=2.72] Suwen Liu et al."Protective effects of hawthorn (Crataegus pinnatifida) polyphenol extract against UVB-induced skin damage by modulating the p53 mitochondrial pathway in vitro and in vivo."J Food Biochem. 2019 Feb;43(2):e12708 24. [IF=7.514] Yongfang Ren et al."Antioxidant activity, stability, in vitro digestion and cytotoxicity of two dietary polyphenols co-loaded by β-lactoglobulin."Food Chem. 2022 Mar;371:131385 25. [IF=7.514] Li Zhao et al."Synergistic inhibitory effects of procyanidin B2 and catechin on acrylamide in food matrix."Food Chem. 2019 Oct;296:94 26. [IF=7.514] Balarabe B. Ismail et al."High-intensity ultrasound processing of baobab fruit pulp: Effect on quality, bioactive compounds, and inhibitory potential on the activity of α-amylase and α-glucosidase."Food Chem. 2021 Nov;361:130144 27. [IF=6.513] Balarabe B. Ismail et al."Ultrasound-assisted adsorption/desorption for the enrichment and purification of flavonoids from baobab (Adansonia digitata) fruit pulp."Ultrason Sonochem. 2020 Jul;65:104980 28. [IF=5.537] Dandan Zhou et al."Metabolic analysis of phenolic profiles reveals the enhancements of anthocyanins and procyanidins in postharvest peach as affected by hot air and ultraviolet C."Postharvest Biol Tec. 2020 Sep;167:111227 29. [IF=5.537] Tiantian Tang et al."A difference of enzymatic browning unrelated to PPO from physiology, targeted metabolomics and gene expression analysis in Fuji apples."Postharvest Biol Tec. 2020 Dec;170:111323 30. [IF=4.952] Ting Zhao et al."The antioxidant property and α-amylase inhibition activity of young apple polyphenols are related with apple varieties."Lwt Food Sci Technol. 2019 Aug;111:252 31. [IF=4.952] Dongxiao Su et al."Impact of thermal processing and storage temperature on the phenolic profile and antioxidant activity of different varieties of lychee juice."Lwt Food Sci Technol. 2019 Dec;116:108578 32. [IF=4.952] Si Tan et al."The effects of drying methods on chemical profiles and antioxidant activities of two cultivars of Psidium guajava fruits."Lwt Food Sci Technol. 2020 Jan;118:108723 33. [IF=4.872] Jie Deng et al."Protective effect of hawthorn extract against genotoxicity induced by benzo()pyrene in C57BL/6 mice."Ecotox Environ Safe. 2020 Sep;200:110761 34. [IF=4.379] Zhang Liang-Liang et al."Chemical composition, antibacterial activity and action mechanism of different extracts from hawthorn (Crataegus pinnatifida Bge.)."Sci Rep-Uk. 2020 Jun;10(1):1-13 35. [IF=3.361] Zhineng Wang et al."Comparison of the phenolic profiles and physicochemical properties of different varieties of thermally processed canned lychee pulp."Rsc Adv. 2020 Feb;10(12):6743-6751 36. [IF=2.72] Meiling Han et al."Phenolic compounds present in fruit extracts of Malus spp. show antioxidative and pro-apoptotic effects on human gastric cancer cell lines."J Food Biochem. 2019 Nov;43(11):e13028 37. [IF=2.19] Suwen Liu et al."Effects of different drying and milling methods on the physicochemical properties and phenolic content of hawthorn fruit powders."J Food Process Pres. 2020 Jun;44(6):e14460 38. [IF=1.296] Han Meiling et al."Analysis of flavonoids and anthocyanin biosynthesis-related genes expression reveals the mechanism of petal color fading of Malus hupehensis (Rosaceae)."Braz J Bot. 2020 Mar;43(1):81-89 39. [IF=1.296] Shen Ting et al."Pigment profile and gene analysis revealed the reasons of petal color difference of crabapples."Braz J Bot. 2021 Jun;44(2):287-296 40. [IF=6.576] Jie Yang et al."Fermentation and Storage Characteristics of “Fuji” Apple Juice Using Lactobacillus acidophilus, Lactobacillus casei and Lactobacillus plantarum: Microbial Growth, Metabolism of Bioactives and in vitro Bioactivities."Front Nutr. 2022; 9: 83 41. 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原花青素 B2 - 简介
原花青素B2是一种天然的化合物，属于花青素类化合物。它是一种稀少的紫红色结晶，具有强烈的色素和抗氧化性质。
原花青素B2的制法常通过提取含有花青素的植物材料，如紫薯、紫甘蓝等。提取后，经过结晶、纯化等工艺步骤，得到纯净的原花青素B2。
原花青素B2的安全性，目前还没有发现对人体健康有害的副作用。在生产和使用过程中，应避免与有毒物质接触，储存于干燥、阴凉的地方，远离火源和高温。另外，个别人群如儿童、孕妇、哺乳期女性等，可能对原花青素B2过敏或不耐受，在使用过程中需注意个体差异。
原花青素B2的制法常通过提取含有花青素的植物材料，如紫薯、紫甘蓝等。提取后，经过结晶、纯化等工艺步骤，得到纯净的原花青素B2。
原花青素B2的安全性，目前还没有发现对人体健康有害的副作用。在生产和使用过程中，应避免与有毒物质接触，储存于干燥、阴凉的地方，远离火源和高温。另外，个别人群如儿童、孕妇、哺乳期女性等，可能对原花青素B2过敏或不耐受，在使用过程中需注意个体差异。
最后更新：2024-04-09 21:54:55
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